Jobs › Massachusetts › Boston › Director, Enterprise Third-Party Risk Management Operations & Governance
Director, Enterprise Third-Party Risk Management Operations & Governance
Vertex Pharmaceuticals is hiring for the job of Director, Enterprise Third-Party Risk Management Operations & Governance, Boston, MA (On-site). This is a Risk job in the governance, risk, and compliance field, with a posted range of $176,000 - $264,000. Review the full details below and apply directly with Vertex Pharmaceuticals.
Job Description General Summary: As a key leader within Strategic Sourcing and Enterprise Third-Party Risk Management (TPRM), the Director, Enterprise Third-Party Risk Management Operations Governance is responsible for ensuring seamless operational execution of the enterprise TPRM program while preparing the organization for future scale and maturity. This role serves as the bridge between strategic program development and operational delivery, partnering closely with TPRM leadership, business stakeholders, Risk SMEs, sourcing teams, and managed service providers (MSPs) to ensure efficient execution, consistent governance, stakeholder engagement, and operational excellence across the third-party risk lifecycle. The Director will focus on integrating existing and emerging TPRM capabilities, strengthening stakeholder partnerships, enhancing governance and reporting, and building scalable operating models that support Vertex s evolving risk management objectives. Key Duties and Responsibilities: Operational Integration Program Delivery Lead operational integration of existing and newly established TPRM processes to create a seamless end-to-end third-party risk experience. Partner with TPRM leadership to translate strategic priorities into operational execution plans and measurable outcomes. Ensure consistent execution and oversight of supplier criticality, risk assessment, issue management, ongoing monitoring, and remediation processes. Identify and remove operational bottlenecks while driving improved efficiency and stakeholder experience. Support implementation and stabilization of expanded TPRM capabilities and operating models. Governance Executive Reporting Own development and execution of TPRM governance routines, including operational reviews, risk escalation forums, and executive reporting. Establish meaningful performance measurements and service-level metrics across the TPRM ecosystem. Develop clear and actionable reporting for senior leadership focused on program effectiveness, risk trends, capacity, and operational health. Ensure alignment between TPRM operational performance and enterprise risk management objectives. Managed Service Provider (MSP) Oversight Scale Readiness Provide leadership oversight of external TPRM service providers and operational partners. Establish performance standards, service expectations, escalation pathways, and continuous improvement mechanisms. Drive operational readiness planning to support increasing assessment volumes, geographic expansion, and future program maturity. Evaluate resource models, workflows, and capabilities required for long-term program scalability. Stakeholder Engagement Partnership Elevate partnerships across Strategic Sourcing, Legal, Compliance, Information Security, Quality, Finance, Enterprise Risk Management, and business functions. Act as a trusted advisor to stakeholders on TPRM operational processes, governance expectations, and risk escalation practices. Drive alignment among risk owners, business stakeholders, and operational teams to ensure consistent decision-making and accountability. Facilitate communication across functions to improve transparency, responsiveness, and overall program effectiveness. Continuous Improvement Operational Excellence Identify opportunities to simplify, standardize, and optimize TPRM processes. Partner with process, technology, and analytics leaders to improve user experience and operational effectiveness. Support implementation of automation, reporting enhancements, and workflow improvements that increase productivity and scalability. Champion operational excellence principles and promote a culture of accountability, service, and continuous improvement. Leadership Lead and develop team members while fostering strong collaboration across the broader TPRM organization. Promote a customer-focused mindset that balances business objectives with effective risk management. Support organizational change efforts as program capabilities continue to evolve. Knowledge and Skills: Strong analytical and project management skills. Exceptional leadership, communication, and stakeholder management skills. Familiarity with third-party risk assessment tools, dashboards, and governance frameworks. Ability to lead cross-functional teams and drive operational excellence. Track record of delivering measurable outcomes through process transformation, automation, and user experience redesign. Thoughtful and active listener; able to think quickly and effectively articulate points of view. Ability to work in collaborative, team environment; ability to cultivate and maintain effective business partner relationships through earned respect and trust Ability to manage multiple priorities while ensuring deliverables are fully met, including more complex and involved projects. Knowledge of regulatory requirements and industry best practices in third-party risk. Education and Experience: Bachelor’s degree in Business, Finance, Risk Management, or related field. Professional certifications (e.g., CRMA, CTPRP, CISM) preferred. Strong analytical and project management skills. Exceptional leadership, communication, and stakeholder management skills. Familiarity with third-party risk assessment tools, dashboards, and governance frameworks. Ability to lead cross-functional teams and drive operational excellence. Track record of delivering measurable outcomes through process transformation, automation, and user experience redesign. Thoughtful and active listener; able to think quickly and effectively articulate points of view. Ability to work in collaborative, team environment; ability to cultivate and maintain effective business partner relationships through earned respect and trust Ability to manage multiple priorities while ensuring deliverables are fully met, including more complex and involved projects. Knowledge of regulatory requirements and industry best practices in third-party risk. At Vertex, we embrace continuous learning and encourage employees to stay informed on advances in AI, technology, automation, and industry trends. We seek talent who bring an external perspective, demonstrate curiosity and sound judgment, and thoughtfully adopt new capabilities that improve decision-making, drive innovation, increase efficiency, and help deliver better outcomes for patients. Pay Range: $176,000 - $264,000 Disclosure Statement: The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law. At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more. Flex Designation: Hybrid-Eligible Or On-Site Eligible Flex Eligibility Status: In this Hybrid-Eligible role, you can choose to be designated as: 1. Hybrid : work remotely up to two days per week; or select 2. On-Site : work five days per week on-site with ad hoc flexibility. Note: The Flex status for this position is subject to Vertex’s Policy on Flex Vertex Program and may be changed at any time. #LI-Hybrid Company Information Vertex is a global biotechnology company that invests in scientific innovation. Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person s race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance vrtx.com
Certifications this role asks for
Studying for one of these? Try the free CISM practice questions in our academy. No signup, no cost.
Location and market context
This job is based in Boston on-site. Local candidates benefit from being close to Vertex Pharmaceuticals's teams and regional hiring market. Confirm the exact in-office expectation and any relocation support with the employer.
About risk management jobs
Risk jobs own the methodology for identifying, assessing, and escalating enterprise, operational, and technology risk. Second-line teams set risk appetite and challenge the first line. Jobs like this one are typically evaluated against frameworks such as enterprise and operational risk frameworks, NIST AI RMF, and risk-appetite and escalation practices.
How to position yourself for this risk management job
Strong candidates emphasize risk assessment methodology, appetite and escalation, cross-functional partnership, and clear reporting to senior leadership and the board. In your resume and outreach, tie your experience to how Vertex Pharmaceuticals would apply enterprise and operational risk frameworks, NIST AI RMF, and risk-appetite and escalation practices, and lead with concrete outcomes rather than duties.
Similar GRC jobs
- Senior Risk Manager · OKX · Dubai, United Arab Emirates
- Business Risk Manager – Growth · N26 · Barcelona
- Sales Manager, Product- Fraud & Risk · Stripe · San Francisco, NYC, Seattle · Remote
- Credit Risk Officer, Energy Trading Credit Risk Management - Vice President · Deutsche Bank · 2 Locations
- Senior Manager – Risk & Regulatory (She/ He/ They) · Capco · Poland - Warsaw
- Emergency Management Specialist (Risk Analyst) · Federal Emergency Management Agency · Washington, District of Columbia
- Data and AI Risk & Ethics Specialist · Defense Media Activity · Fort Meade, Maryland
- Chief Risk Office – Market Risk Manager (Metals) – VP · Deutsche Bank · Singapore, One Raffles Quay
More jobs at Vertex Pharmaceuticals
- Director Global Trade Compliance · Vertex Pharmaceuticals · Boston, MA
- Senior Director - Quality Data, Digital Systems & Compliance · Vertex Pharmaceuticals · Boston, MA
- Director, Regulatory Affairs CMC · Vertex Pharmaceuticals · Boston, MA
- Director, Compliance Business Partner · Vertex Pharmaceuticals · Boston, MA
- DTE Audit & Compliance Manager (Sr. Principal Analyst) · Vertex Pharmaceuticals · Boston, MA
- Director CMC Quality Compliance (Hybrid) · Vertex Pharmaceuticals · Boston, MA
More GRC jobs in Boston
- Supervisory Auditor (Performance) · Office of Inspector General · Boston, Massachusetts
- Auditor · Executive Office for U.S. Attorneys and the Office of the U.S. Attorneys · Boston, Massachusetts
- Global Head of Data & AI Governance & Oversight, SVP · State Street · Boston, MA
- Director, Regulatory Data Management (Boston, MA) · Vertex Pharmaceuticals · Boston, MA
- Associate Director, CMC Quality Compliance and Inspection Readiness (Hybrid) · Vertex Pharmaceuticals · Boston, MA
- Director, Regulatory Labeling Strategy (Remote-Eligible) · Vertex Pharmaceuticals · Boston, MA
Hiring for Risk?
Reach candidates who are already searching for this role, not a general audience. Your posting appears on this page, in the job alerts, and across the GRC Careers network.
Post a job Pricing from $99 · About GRC Careers · Hiring toolkit
Want to be next in a job like this?
Jobs like Director, Enterprise Third-Party Risk Management Operations & Governance in Boston, MA open regularly. Be first to know, privately. No current employer ever sees you looking.
Employer, or see something wrong with this posting? Report this posting and we will review it promptly.